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ZO Radical Night Retinol
Radical Night Retinol is a 1% encapsulated retinol with vitamins A, C and E. It is a night treatment for texture, uneven pigment and lines.
$2001% retinol night treatment
Ships directly from ZO Skin Health. ZO sells its products only through clinical professionals, and our link connects your order to The Naderi Center.

What is ZO Radical Night Retinol?
Radical Night Retinol is a 1% retinol night treatment from ZO Skin Health, made for all skin types, anti-aging. Key ingredients include 1% encapsulated retinol, Vitamins C, E and A, Minimizes the appearance of redness to restore a more youthful skin tone, Glycerin, sunflower seed oil, plukenetia volubilis seed oil.
Radical Night Retinol at a Glance
- Type
- 1% retinol night treatment
- Best for
- all skin types, anti-aging
- Key ingredients
- 1% encapsulated retinol, Vitamins C, E and A, Minimizes the appearance of redness to restore a more youthful skin tone, Glycerin, sunflower seed oil, plukenetia volubilis seed oil, Hydrate and support the skin barrier with essential lipids
- When to use
- PM
- Price
- $200 on ZO’s official store
Key Ingredients in Radical Night Retinol
- 1% encapsulated retinol: diminishes the appearance of fine lines + wrinkles while improving skin smoothness
- Vitamins C, E and A: provides additional antioxidant protection
- Minimizes the appearance of redness to restore a more youthful skin tone
- Glycerin, sunflower seed oil, plukenetia volubilis seed oil
- Hydrate and support the skin barrier with essential lipids
What Does Radical Night Retinol Do?
- Helps improve the appearance of skin’s brightness and provides a more even skin tone
- Helps calm and soothe the skin
- Helps minimize the appearance of fine lines and wrinkles
How to Use Radical Night Retinol
- Radical Night Retinol is a high-potency retinol treatment. If you have not been using retinol, begin use gradually.
- Following cleansing, apply to clean, dry skin twice a week.
- Increase frequency to alternate days.
- Then, increase use to every day as tolerated.
Before and after a laser treatment, peel or microneedling, follow the instructions we give you for when to stop and restart active products like this one. If you are pregnant or breastfeeding, ask us first.
Pairs Well With Radical Night Retinol



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Radical Night Retinol FAQs
What is ZO Radical Night Retinol best for?
Radical Night Retinol is a 1% retinol night treatment best for all skin types, anti-aging.
How do I use ZO Radical Night Retinol?
Radical Night Retinol is a high-potency retinol treatment. If you have not been using retinol, begin use gradually. Following cleansing, apply to clean, dry skin twice a week. Increase frequency to alternate days.
Is it normal for retinol to cause redness or flaking at first?
Some dryness, flaking or redness is common in the first weeks of any retinol. Start slowly, follow the directions on this page, and tell us if irritation does not settle. If you are pregnant, trying to become pregnant or breastfeeding, ask us before using retinol.
How much does ZO Radical Night Retinol cost?
Radical Night Retinol is $200 on ZO’s official store. Ordering through our link connects your order to The Naderi Center, and ZO ships it directly to you.
Where can I buy ZO Radical Night Retinol?
ZO sells its products only through clinical professionals and its official website. Order through our link to ZO’s store and it ships to your door.
Ready to Order?
Order on ZO’s official store through our link, and ZO ships it directly to you.
Medically reviewed by Dr. Shervin Naderi, double board-certified facial plastic surgeon. Last updated October 2026. ZO Skin Health product details and study results are from ZO Skin Health. Orders placed through our links are fulfilled by ZO Skin Health and connected to The Naderi Center.
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