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ZO Hydrating Crème
Hydrating Crème soothes dry, irritated and post-treatment skin. It calms the look of redness and itching while restoring moisture.
$125Barrier-repair moisturizer
Ships directly from ZO Skin Health. ZO sells its products only through clinical professionals, and our link connects your order to The Naderi Center.

What is ZO Hydrating Crème?
Hydrating Crème is a barrier-repair moisturizer from ZO Skin Health, made for dry to sensitized skin, skin hydration, post-procedure treatment, barrier strengthening and resilience. Key ingredients include Ophiopogon Japonicus Root Extract, Myristoyl Pentapeptide-11, ZOX12, Colloidal Oatmeal. Apply as the last step in your AM + PM routine. Use SPF in the morning.
Hydrating Crème at a Glance
- Type
- Barrier-repair moisturizer
- Best for
- dry to sensitized skin, skin hydration, post-procedure treatment, barrier strengthening and resilience
- Key ingredients
- Ophiopogon Japonicus Root Extract, Myristoyl Pentapeptide-11, ZOX12, Colloidal Oatmeal
- When to use
- Apply as the last step in your AM + PM routine. Use SPF in the morning.
- Where it goes
- ZO Hydrating Crème is a supplementary hydrator applied as needed, after your Strengthen + Correct products. In the morning, follow with your ZO SPF product. For intensive recovery during post-procedure phases, use as directed by your physician.
- Price
- $125 on ZO’s official store
Key Ingredients in Hydrating Crème
- Ophiopogon Japonicus Root Extract: helps restore skin barrier function and hydration
- Myristoyl Pentapeptide-11: supports overall skin health
- ZOX12: exclusive antioxidant complex of encapsulated vitamins A, C, and E delivers 12 hours of defense against free radical damage from environmental aggressors
- Colloidal Oatmeal: provides fast-acting skin soothing benefits
How to Use Hydrating Crème
- Apply as the last step in your AM + PM routine. Use SPF in the morning.
- Apply to the face and neck.
What to Expect
Replenishes skin’s natural moisture to aid in skin recovery.
What ZO’s Study Found
- 90% saw a visible improvement in skin dryness by week 8
- 90% saw a visible improvement in skin texture and smoothness by week
- 85% reported that skin appeared less red by week 12
- 87% reported a reduction in itching from dryness by week 8
Results reported by ZO Skin Health. Individual results vary.
Pairs Well With Hydrating Crème



Hydrating Crème FAQs
What is ZO Hydrating Crème best for?
Hydrating Crème is a barrier-repair moisturizer best for dry to sensitized skin, skin hydration, post-procedure treatment, barrier strengthening and resilience.
How do I use ZO Hydrating Crème?
Apply as the last step in your AM + PM routine. Use SPF in the morning. Apply to the face and neck.
Where does Hydrating Crème go in my routine?
ZO Hydrating Crème is a supplementary hydrator applied as needed, after your Strengthen + Correct products. In the morning, follow with your ZO SPF product. For intensive recovery during post-procedure phases, use as directed by your physician.
How much does ZO Hydrating Crème cost?
Hydrating Crème is $125 on ZO’s official store. Ordering through our link connects your order to The Naderi Center, and ZO ships it directly to you.
Where can I buy ZO Hydrating Crème?
ZO sells its products only through clinical professionals and its official website. Order through our link to ZO’s store and it ships to your door.
Ready to Order?
Order on ZO’s official store through our link, and ZO ships it directly to you.
Medically reviewed by Dr. Shervin Naderi, double board-certified facial plastic surgeon. Last updated October 2026. ZO Skin Health product details and study results are from ZO Skin Health. Orders placed through our links are fulfilled by ZO Skin Health and connected to The Naderi Center.
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Visit Us in Reston, VA or Chevy Chase, MD
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Friday, 9 AM to 4 PM
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Pavilion II, Suite 551
Reston, VA 20190
(703) 481-0002
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Friday, 9 AM to 4 PM
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