Home / ZO Skin Health / Peptide Facial Refining Concentrate

ZO Skin Health · Serum

ZO Peptide Facial Refining Concentrate

Peptide Facial Refining Concentrate smooths expression lines and helps restore the look of lost volume. It works on its own and alongside injectable treatments.

$265Concentrated peptide serum

Ships directly from ZO Skin Health. ZO sells its products only through clinical professionals, and our link connects your order to The Naderi Center.

ZO Skin Health Peptide Facial Refining Concentrate

What is ZO Peptide Facial Refining Concentrate?

Peptide Facial Refining Concentrate is a concentrated peptide serum from ZO Skin Health, made for all skin types, lift and definition, volume and smoothness, lines and wrinkles, pairing with injectables. Key ingredients include Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Refining Peptide Complex, Volumizing Tripeptide. Use AM + PM after Getting Skin Ready (cleanse, exfoliate, tone).

At a Glance

Peptide Facial Refining Concentrate at a Glance

Type
Concentrated peptide serum
Best for
all skin types, lift and definition, volume and smoothness, lines and wrinkles, pairing with injectables
Key ingredients
Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Refining Peptide Complex, Volumizing Tripeptide, ZPOLY Complex
When to use
Use AM + PM after Getting Skin Ready (cleanse, exfoliate, tone).
Where it goes
Apply after Getting Skin Ready as the Correct step of your ZO system. Follow with SPF in the morning.
Price
$265 on ZO’s official store
What’s Inside

Key Ingredients in Peptide Facial Refining Concentrate

  • Acetyl Octapeptide-3: targets the appearance of dynamic lines + wrinkles, especially around the forehead + eye area, helping this anti-wrinkle peptide serum deliver visibly smoother skin
  • Acetyl Hexapeptide-8: provides greater precision in smoothing the appearance of deeper dynamic + static wrinkles
  • Refining Peptide Complex: A key component of this sculpting peptide serum, supporting a more visibly refined facial geometry
  • Volumizing Tripeptide: supports hyaluronic acid production for fuller, plumper-looking skin
  • ZPOLY Complex: soothes visible redness + reinforces the skin barrier, helping maintain comfort and resilience while optimizing results from this high-performance anti-wrinkle serum
Step by Step

How to Use Peptide Facial Refining Concentrate

  1. Use AM + PM after Getting Skin Ready (cleanse, exfoliate, tone).
  2. Apply to clean, dry skin. Spread Peptide Facial Refining Concentrate evenly over the face, using upward and outward motions until absorbed.
ZO Study Results

What ZO’s Study Found

  • 92% saw a reduction in the appearance of fine lines
  • 82% saw a reduction in visible forehead wrinkles
  • 96% said their skin was smoother looking
  • 84% said they had a visibly younger-looking facial geometry

Results reported by ZO Skin Health. Individual results vary.

Build Your Routine

Complete Your Routine

ZO Skin Health Growth Factor Serum
Serum

Growth Factor Serum

$200
ZO Skin Health Firming Serum
Serum

Firming Serum

$265
ZO Skin Health Getting Skin Ready Program
Program Kit

Getting Skin Ready Program

$110

Not sure what fits your skin? Take the ZO Skin Quiz, see the ZO kits or browse every brand we carry.

Questions Patients Ask

Peptide Facial Refining Concentrate FAQs

What is ZO Peptide Facial Refining Concentrate best for?

Peptide Facial Refining Concentrate is a concentrated peptide serum best for all skin types, lift and definition, volume and smoothness, lines and wrinkles, pairing with injectables.

How do I use ZO Peptide Facial Refining Concentrate?

Use AM + PM after Getting Skin Ready (cleanse, exfoliate, tone). Apply to clean, dry skin. Spread Peptide Facial Refining Concentrate evenly over the face, using upward and outward motions until absorbed.

Where does Peptide Facial Refining Concentrate go in my routine?

Apply after Getting Skin Ready as the Correct step of your ZO system. Follow with SPF in the morning.

How much does ZO Peptide Facial Refining Concentrate cost?

Peptide Facial Refining Concentrate is $265 on ZO’s official store. Ordering through our link connects your order to The Naderi Center, and ZO ships it directly to you.

Where can I buy ZO Peptide Facial Refining Concentrate?

ZO sells its products only through clinical professionals and its official website. Order through our link to ZO’s store and it ships to your door.

Ready to Order?

Order on ZO’s official store through our link, and ZO ships it directly to you.

Medically reviewed by Dr. Shervin Naderi, double board-certified facial plastic surgeon. Last updated October 2026. ZO Skin Health product details and study results are from ZO Skin Health. Orders placed through our links are fulfilled by ZO Skin Health and connected to The Naderi Center.

Our Offices

Visit Us in Reston, VA or Chevy Chase, MD

Two offices serving patients across the Washington, DC area, in Northern Virginia and Montgomery County, Maryland.

Areas we serve
  • Washington, DC
  • McLean
  • Great Falls
  • Vienna
  • Reston
  • Arlington
  • Alexandria
  • Bethesda
  • Chevy Chase
  • Potomac

Maryland

5454 Wisconsin Ave,
Suite 1655
Chevy Chase, MD 20815
(301) 222-2020

Monday to Thursday, 9 AM to 5 PM
Friday, 9 AM to 4 PM
Get directions

Virginia

1850 Town Center Parkway,
Pavilion II, Suite 551
Reston, VA 20190
(703) 481-0002 

Monday to Thursday, 9 AM to 5 PM
Friday, 9 AM to 4 PM
Get directions