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ZO Skin Health · Retinol

ZO Clear Renewal

Clear Renewal combines 0.3% encapsulated retinol with salicylic acid. It reduces the look of post-blemish marks and excess oil for smoother, clearer skin.

$170Retinol for blemish-prone skin

Ships directly from ZO Skin Health. ZO sells its products only through clinical professionals, and our link connects your order to The Naderi Center.

ZO Skin Health Clear Renewal

What is ZO Clear Renewal?

Clear Renewal is a retinol for blemish-prone skin from ZO Skin Health, made for blemish-prone skin, anti-aging, uneven skin texture, reducing inflammation, breakouts. Key ingredients include Salicylic Acid 1%, Bakuchiol, ZO-RRS2, Potassium Azeloyl Diglycinate. Apply AM and/or PM.

At a Glance

Clear Renewal at a Glance

Type
Retinol for blemish-prone skin
Best for
blemish-prone skin, anti-aging, uneven skin texture, reducing inflammation, breakouts
Key ingredients
Salicylic Acid 1%, Bakuchiol, ZO-RRS2, Potassium Azeloyl Diglycinate, Rose Canina Fruit Extract, Cetyl Tranexamate Mesylate
When to use
Apply AM and/or PM
Where it goes
After completing the Getting Skin Ready regimen to cleanse, exfoliate, and tone the skin, apply Clear Renewal as Step 2 of your ZO regimen, followed with a broad-spectrum sunscreen with SPF 30 or higher as the final step in the morning.
Price
$170 on ZO’s official store
What’s Inside

Key Ingredients in Clear Renewal

  • Salicylic Acid 1%: gently exfoliates and helps reduce the appearance of pore congestion.
  • Bakuchiol: works synergistically with retinol to improve the look of uneven skin tone.
  • ZO-RRS2: exclusive plant stem cell complex that provides powerful antioxidant benefits.
  • Potassium Azeloyl Diglycinate: helps refine the appearance of pores by reducing the look of excess oil, supporting skin clarity, and promoting a smoother, more balanced-looking complexion.
  • Rose Canina Fruit Extract: minimizes oil on the surface of the skin.
  • Cetyl Tranexamate Mesylate: helps visibly brighten the appearance of skin and promote a more even-looking complexion.
Step by Step

How to Use Clear Renewal

  1. Apply AM and/or PM.
  2. Apply one pump to clean, dry skin once per day for the first week and twice per day thereafter.

What to Expect

Visible reduction in the appearance of post-blemish marks and excess surface oil, refined look of skin texture for a smoother complexion. What to Avoid Avoid excessive sun exposure. Avoid using on irritated or compromised skin and applying immediately after aggressive procedures (chemical peels, laser treatment, etc.). Consult a physician prior if using products with benzoyl peroxide or salicylic acid, topical antibiotics or oral isotretinoin.

Before and after a laser treatment, peel or microneedling, follow the instructions we give you for when to stop and restart active products like this one. If you are pregnant or breastfeeding, ask us first.

Build Your Routine

Pairs Well With Clear Renewal

ZO Skin Health Getting Skin Ready Program
Program Kit

Getting Skin Ready Program

$110
ZO Skin Health Hydrating Crème
Moisturizer

Hydrating Crème

$125
ZO Skin Health Daily Sheer Broad-Spectrum SPF 50
Sunscreen

Daily Sheer Broad-Spectrum SPF 50

$48

Not sure what fits your skin? Take the ZO Skin Quiz, see the ZO kits or browse every brand we carry.

Questions Patients Ask

Clear Renewal FAQs

What is ZO Clear Renewal best for?

Clear Renewal is a retinol for blemish-prone skin best for blemish-prone skin, anti-aging, uneven skin texture, reducing inflammation, breakouts.

How do I use ZO Clear Renewal?

Apply AM and/or PM. Apply one pump to clean, dry skin once per day for the first week and twice per day thereafter.

Where does Clear Renewal go in my routine?

After completing the Getting Skin Ready regimen to cleanse, exfoliate, and tone the skin, apply Clear Renewal as Step 2 of your ZO regimen, followed with a broad-spectrum sunscreen with SPF 30 or higher as the final step in the morning.

Is it normal for retinol to cause redness or flaking at first?

Some dryness, flaking or redness is common in the first weeks of any retinol. Start slowly, follow the directions on this page, and tell us if irritation does not settle. If you are pregnant, trying to become pregnant or breastfeeding, ask us before using retinol.

How much does ZO Clear Renewal cost?

Clear Renewal is $170 on ZO’s official store. Ordering through our link connects your order to The Naderi Center, and ZO ships it directly to you.

Where can I buy ZO Clear Renewal?

ZO sells its products only through clinical professionals and its official website. Order through our link to ZO’s store and it ships to your door.

Ready to Order?

Order on ZO’s official store through our link, and ZO ships it directly to you.

Medically reviewed by Dr. Shervin Naderi, double board-certified facial plastic surgeon. Last updated October 2026. ZO Skin Health product details and study results are from ZO Skin Health. Orders placed through our links are fulfilled by ZO Skin Health and connected to The Naderi Center.

Our Offices

Visit Us in Reston, VA or Chevy Chase, MD

Two offices serving patients across the Washington, DC area, in Northern Virginia and Montgomery County, Maryland.

Areas we serve
  • Washington, DC
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  • Great Falls
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  • Reston
  • Arlington
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  • Bethesda
  • Chevy Chase
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Maryland

5454 Wisconsin Ave,
Suite 1655
Chevy Chase, MD 20815
(301) 222-2020

Monday to Thursday, 9 AM to 5 PM
Friday, 9 AM to 4 PM
Get directions

Virginia

1850 Town Center Parkway,
Pavilion II, Suite 551
Reston, VA 20190
(703) 481-0002 

Monday to Thursday, 9 AM to 5 PM
Friday, 9 AM to 4 PM
Get directions