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ZO Complexion Clarifying Serum
Complexion Clarifying Serum is a water-based serum that cuts surface oil, congestion and visible redness. It is a daily step for oily and blemish-prone skin.
$125Oil-balancing daily serum
Ships directly from ZO Skin Health. ZO sells its products only through clinical professionals, and our link connects your order to The Naderi Center.

What is ZO Complexion Clarifying Serum?
Complexion Clarifying Serum is an oil-balancing daily serum from ZO Skin Health, made for all skin types, oily + blemish-prone skin, redness. Key ingredients include Water-Soluble Salicylic Acid, ZO-RRS2, ZPOLY.
Complexion Clarifying Serum at a Glance
- Type
- Oil-balancing daily serum
- Best for
- all skin types, oily + blemish-prone skin, redness
- Key ingredients
- Water-Soluble Salicylic Acid, ZO-RRS2, ZPOLY
- When to use
- AM + PM
- Price
- $125 on ZO’s official store
Key Ingredients in Complexion Clarifying Serum
- Water-Soluble Salicylic Acid: powerfully decongests skin + refines the look of pores in a gentle, non-drying delivery
- ZO-RRS2: exclusive plant stem cell complex that soothes visible redness while neutralizing damaging free radicals
- ZPOLY: plant-derived polysaccharide complex that supports skin’s protective barrier + helps minimize signs of premature skin aging
What Does Complexion Clarifying Serum Do?
- Proven to decongest skin + reduce shine in 2 weeks.
- Minimizes excess sebum with daily use, while providing optimal hydration for a range of skin types.
- Reduces visible redness for a more uniform complexion.
- Light, water-gel formula layers easily.
- Features a unique dropper that fills automatically for ease of application.
How to Use Complexion Clarifying Serum
- Apply to clean, dry skin morning and night.
Before and after a laser treatment, peel or microneedling, follow the instructions we give you for when to stop and restart active products like this one. If you are pregnant or breastfeeding, ask us first.
What ZO’s Study Found
- 98% said it provides decongesting benefits without irritation
- 86% said it rebalances combination skin
- 86% said it reduces the appearance of redness + blotchiness
- 95% said their skin is healthy looking
Results reported by ZO Skin Health. Individual results vary.
Pairs Well With Complexion Clarifying Serum



Not sure what fits your skin? Take the ZO Skin Quiz, see the ZO kits or browse every brand we carry.
Complexion Clarifying Serum FAQs
What is ZO Complexion Clarifying Serum best for?
Complexion Clarifying Serum is an oil-balancing daily serum best for all skin types, oily + blemish-prone skin, redness.
How do I use ZO Complexion Clarifying Serum?
Apply to clean, dry skin morning and night.
How much does ZO Complexion Clarifying Serum cost?
Complexion Clarifying Serum is $125 on ZO’s official store. Ordering through our link connects your order to The Naderi Center, and ZO ships it directly to you.
Where can I buy ZO Complexion Clarifying Serum?
ZO sells its products only through clinical professionals and its official website. Order through our link to ZO’s store and it ships to your door.
Ready to Order?
Order on ZO’s official store through our link, and ZO ships it directly to you.
Medically reviewed by Dr. Shervin Naderi, double board-certified facial plastic surgeon. Last updated October 2026. ZO Skin Health product details and study results are from ZO Skin Health. Orders placed through our links are fulfilled by ZO Skin Health and connected to The Naderi Center.
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